Antinociceptive effects of purified Curcuma longa in mice

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Curcuma longa

Description Curcuma longa, a perennial herb and member of the Zingiberaceae (ginger) family, grows to a height of three to five feet and is cultivated extensively in Asia, India, China, and other countries with a tropical climate. It has oblong, pointed leaves and funnel-shaped yellow flowers.1 The rhizome, the portion of the plant used medicinally, is usually boiled, cleaned, and dried, yieldi...

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Choleretic Effect of Curcuma longa and Verapamil in Mice

Choleretic drugs are used in some conditions e.g., fat maldigestion. Verapamil is a calcium channel blocker, which inhibits p-glycoprotein (P-gp) and may affect bile accumulation. Curcuma longa is traditionally used for treatment of maldigestion and as food additive. In this study, the effect of verapamil and Curcuma longa was compared on bile accumulation in gall bladder of mice. This simple a...

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Pharmacology of Curcuma longa.

The data reviewed indicate that extracts of Curcuma longa exhibit anti-inflammatory activity after parenteral application in standard animal models used for testing anti-inflammatory activity. It turned out that curcumin and the volatile oil are at least in part responsible for this action. It appears that when given orally, curcumin is far less active than after i.p. administration. This may b...

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Preparation and physicochemical evaluation of topical formulations of purified curcuminoids from Curcuma longa rhizome

Background and objectives: The purpose of this study was optimization of semisolid topical formulation from ethanol extract of turmeric and evaluation of rheological characterization and investigation of physicochemical control tests. Methods: The ethanolic extract was prepared with Soxhlet method and the compounds were isolated with silica gel column chromatog...

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Antischistosomal and liver protective effects of Curcuma longa extract in Schistosoma mansoni infected mice.

With a view to clarify the induction of the "Crabtree consequence" in liver cells of S. mansoni infected mice, the curative effect of oil extract of C. longa was tested and compared to praziquantel (PZQ) the effective drug against all schistosome species occurring in man. Protein, glucose, glucose-6-phopsphatase, AMP-deaminase, adensoine deaminase, urea concentration, pyravate kinase (PK), phos...

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ژورنال

عنوان ژورنال: International Journal of Basic and Clinical Pharmacology

سال: 2016

ISSN: 2319-2003

DOI: 10.18203/2319-2003.ijbcp20160766